What is the MAOI?

MAOIs were the initial kind of antidepressant established and ended up being widely utilized in the 1950s. A monoamine oxidase inhibitor is a kind of antidepressant medicine.

In addition to treating anxiety, MAOIs are sometimes utilized to treat such conditions as:

Bipolar illness

Social anxiousness disorder

Panic attack

Trauma or PTSD

Parkinson’s illness

Consuming problems, consisting of bulimia or anorexia

Various other psychiatric problems

MAOIs balance the level of particular chemicals in the brain by preventing the enzyme referred to as monoamine oxidase.

The following medicines are instances of MAOIs:

  • Isocarboxazid or Marplan
  • Selegiline or Emsam
  • Phenelzine or Nardil
  • Tranylcypromine or Parnate

MAOIs were the very first sort of antidepressant created, as well as came to be widely made use of in the 1950s.

Today, a medical professional generally prescribes an MAOI just when other antidepressants fail, since newer medicines are commonly extra reliable as well as have fewer adverse effects.

MAOI Side Effects

There is a threat of severe negative effects, particularly when MAOIs are combined with particular drugs or food.

Some adverse effects of MAOIs include:

  • Dry mouth
  • Diarrhea or irregular bowel movements
  • Queasiness
  • Sleepiness
  • Sleeping disorders or other sleep disruption
  • Headache
  • Anxiety
  • Lightheadedness
  • Skin responses
  • Reduced blood pressure
  • Minimized decreased or libido sex-related capacity
  • Spontaneous muscle mass jerks or muscular tissue pains
  • Weight gain
  • Tingling feeling of the skin
  • Difficulty urinating

MAOIs, like all antidepressants, also carry a black-box warning about the capacity for suicidal actions and thoughts.

In research, antidepressants increased the danger of suicidal tendencies in some children as well as young people with anxiety or psychological problems.

MAOIs as well as Medication Communications

MAOIs can create serious responses if you take them with particular other medicines.

Make sure to tell your doctor as well as a pharmacist all the medicines you’re taking prior to you take an MAOI.

This includes prescriptions, as well as over-the-counter drugs, vitamins, as well as other nutritional supplements, protein powders or dietary drinks, etc., organic solutions, as well as creational drugs or unlawful.


Certain beverages and foods can trigger dangerous responses if they’re taken with an MAOI.

Your medical professional will most likely tell you to prevent foods that contain high levels of dopamine, tyramine, and tryptophan.

Some restricted foods might include:

  • Aged cheeses
  • Cured meats and specific various other meat products
  • Yogurt
  • Fermented sausages such as salami, pepperoni, as well as bologna
  • Anchovies
  • Hen or beef liver
  • Caviar
  • Herring
  • Draft red wine as well as beer
  • Shrimp paste
  • Specific liqueurs
  • Fermented soy items, such as miso, soy sauce, or tofu
  • Specific fruits, such as bananas, dried fruits, raspberries, or overripe fruits
  • Sauerkraut
  • Delicious chocolates
  • Fava beans
  • Caffeinated drinks, such as tea, coffee, or soda pop

Talk with your medical professional concerning all dietary limitations prior to taking an MAOI, as well as make sure you comprehend which foods as well as drinks to prevent

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